Explanation:
Let p be the frequency of LM Allele and q is the frequency of LN Allele
Two alleles are Co-dominant
and p=0.8
so q=1-p=1-0.8=0.2
and inbreeding coefficient or F=0.05 (it is the degree to which two alleles are more likely to be homozygous rather than heterozygous)
The frequency of Homozygotes LMLM = (1-F) p2 +Fp
=p2-Fp2+Fp
=p2+Fp(1-p)
=p2+Fpq
Therefore, The frequency of Homozygotes LMLM in the Eskimo population will be
f(LMLM)= (0.8)2 + 0.05 (0.8) (0.2)
=0.648
Similarly The frequency of Homozygotes LNLN = q2+Fpq
or f(LNLN) = (0.2)2+0.05 (0.8) (0.2)
=0.048
And The frequency of Heterozygotes LMLN =2pq (1-F)
f(LMLN) = 2 (0.8)(0.2) (1-0.05)
=0.304
The expected frequencies of different blood types are
f(MM)=0.648, f(MN)=0.304, f(NN)=0.048