Chemistry
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Quinine (c20h24n2o2) is the most important alkaloid derived from cinchona bark.

Quinine (c20h24n2o2) is the most important alkaloid derived from cinchona bark. it is used as an antimalarial drug. for quinine pkb1 = 5.1 and pkb2 = 9.7 (pkb = −log( only 1.0 g of quinine will dissolve in 1900.0 ml of water. calculate the ph of saturated aqueous solution of quinine. consider only the reaction q + h2o equilibrium reaction arrow qh + + oh? described by pkb1, where q = quinine.
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erenackermanlevijaeg
erenackermanlevijaeg
5,0(61 marks)

The pH of saturated solution of the quinine is 10.05

Explanation:

Quinine (Q) is C20H24N2O2 has a molar mass of 324.4 g/mol

Q can behave as a weak base. Kb and pKb can be calculated for weak bases

pKb1 is to be considered when solving the question.

pKb1 = 5.1

Step 1 : Calculate the Kb of Quinine

            pKb1 = - log [kb]

                5.1  = - log [kb]

                take Antilog of both side

             [kb] = 7.94 x 10∧-6

Step 2: Calculate the concentration of saturated solution of Q in mol/dm3

           From the question, 1900 ml of solution contains 1 g of Q

           Therefore,  1000 ml of solution will contain........... x g of Q

           x = 1000 /1900

           x = 0.526 g in 1 dm3

In calculating concentration in mol/dm3,

Concentration in mol/dm3 = concentration in g /dm3 divided by molar mass

Molar mass of Q = 324.4

Concentration in mol/dm = 0.526 /324.4

                                         = 0.0016 mol/dm3

Step 3: Calculating the Concentration of OH-

            At Equilibrium, Kb = x² / 0.0016

            7.94 x 10∧-6 = x² / 0.0016

            x = √ 0.0016 × 7.94 x 10∧-6

            x = 1. 127 × 10∧-4 mol/dm3

The concentration of OH- = 1. 127 × 10∧-4 mol/dm

Step 4:  Calculating the pH of Quinine

           Recall, pOH = - log [OH-]

           pOH = - log [1. 127 × 10∧-4]

           pOH = 3.948

           Also recall that pH + pOH = 14

           pH = 14 - 3.948

           pH = 10.05

           


Quinine (c20h24n2o2) is the most important alkaloid derived from cinchona bark. it is used as an ant
Quinine (c20h24n2o2) is the most important alkaloid derived from cinchona bark. it is used as an ant
cadenm81
cadenm81
4,7(76 marks)
It is in orbit around the Sun.
It has sufficient mass to assume hydrostatic equilibrium (a nearly round shape).
It has “cleared the neighborhood” around its orbit.

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