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Using prescription sedatives and tranquilizers with other substances — particularly alcohol — can slow breathing, or slow both the heart and respiration, and possibly lead to death. Continued use can lead to physical dependence and — when use is reduced or stopped abruptly — withdrawal symptoms may occur.

Explanation: it should be number three or the third one down, slow breathing, and the heart, and death.

Much of this information comes through the sensory organs: the eyes, ears, nose, tongue, and skin. Specialized cells and tissues within these organs receive raw stimuli and translate them into signals the nervous system can use.

Explanation: